CHARLOTTE, N.C. (AP) - Louisville's suffocating defense has coach Rick Pitino a step away from a sixth trip to the Final Four.

Earl Clark scored 17 points and had 12 rebounds, and Pitino's mix of defenses made life miserable for Tennessee in a 79-60 win Thursday to put the third-seeded Cardinals in the East Regional final.

Pitino, who has won two NCAA titles and has taken three schools to the Final Four, has Louisville playing its best basketball of the season when it counts the most. After two blowout wins last weekend, Pitino's signature zone and pressure limited the high-scoring Volunteers to 34-percent shooting. The veteran coach improved to 8-0 in regional semifinals and secured a date with top-seed North Carolina on Saturday night.

Terrence Williams and Andre McGee each added 13 points and David Padgett had 10 points and eight rebounds for Louisville (27-8), which nearly blew all of a 16-point first half lead, only to take control midway through the second half and keep alive its hopes for a second Final Four berth in four years.

Chris Lofton scored 15 points for Tennessee, but hit only 3 of 15 shots in his final game with the Volunteers (31-5), who have never advanced beyond the round of 16.