BLACKSBURG, Va. – Reggie Ball and his teammates made their second consecutive visit to Virginia Tech a success, jumping out to a big lead and avenging last year’s blowout loss with a 38-27 Saturday.

With Ball finding receivers Calvin Johnson and James Johnson with ease, and mixing in enough of his own running to keep the No. 11 Hokies guessing, the Yellow Jackets (4-1, 2-0 ACC) led 21-0 after just 10:48. Ball finished 9-for-16 for 176 yards with two interceptions.

No. 1 Ohio State 38, No. 13 Iowa 17

IOWA CITY, Iowa – The toughest part of Ohio State’s schedule is behind the Buckeyes.

And Troy Smith and Co. handled it with ease. Smith threw for 186 yards and four touchdowns and No. 1 Ohio State picked up its second road win over a ranked opponent by manhandling No. 13 Iowa 38-17 Saturday night.

No. 3 Southern California 28, Washington St. 22

PULLMAN, Wash. – Steve Smith responded to the loss of All-American Dwayne Jarrett with a career-high 11 catches for 186 yards and two second-half touchdowns, and No. 3 Southern California survived a scare from Washington State with a 28-22 victory Saturday night.

No. 5 Florida 28, Albama 13

GAINESVILLE, Fla. – Florida coach Urban Meyer learned a lot last year at Alabama, most noticeably that defense can win games in the Southeastern Conference.

Ryan Smith had two interceptions, Reggie Nelson returned another pick for a touchdown and the fifth-ranked Gators beat the Crimson Tide 28-13 on Saturday to avenge last season’s most embarrassing loss.

No. 6 Michigan 28, Minnesota 14

MINNEAPOLIS – The Little Brown Jug is headed back to Ann Arbor.

Chad Henne got the sixth-ranked Wolverines off to a fast start with three touchdown passes in the first half and Michigan hung on for a 28-14 victory over Minnesota on Saturday night.

No. 7 Texas 56, Sam Houston State 3

AUSTIN, Texas – Henry Melton ran for two touchdowns, Colt McCoy passed for two more and No. 7 Texas emptied its bench and still piled up the points on Division I-AA Sam Houston State in a 56-3 win Saturday night.

No. 9 LSU 48, Mississippi St. 17

BATON ROUGE, La. – JaMarcus Russell threw for 330 yards and three TDs and matched a school record with 14 consecutive completions for LSU in a game delayed nearly an hour by a thunderstorm.

Russell threw three touchdown passes and completed 18 of 20 passes without an interception.

No. 12 Notre Dame 35, Purdue 21

SOUTH BEND, Ind. – Brady Quinn threw for 316 yards and two touchdowns and Darius Walker ran for 146 yards as the Irish played their best offensive game of the season. Notre Dame withstood a big day by Curtis Painter and the Boilermakers’ offense.

No. 14 Oregon 48, Arizona St 13

TEMPE, Ariz. – The Ducks came to the desert aiming to prove their controversial victory over Oklahoma two weeks ago was no fluke. Mission accomplished.

Oregon (4-0, 2-0 Pac-10) used a balanced attack and a relentless defense to crush Arizona State (3-2, 0-2). l

No. 15 Tennessee 41, Memphis 7

MEMPHIS, Tenn. – Erik Ainge threw four touchdown passes and the Vols (4-1) had an easy time beating their cross-state rival.

Ainge, pulled early in the fourth quarter, completed 23 of 27 passes for 324 yards, including two TD tosses to Jayson Swain and an 84-yarder to Robert Meachem. His other scoring pass was a 7-yarder to Bret Smith.

No. 18 Clemson 51, Louisiana Tech 0

CLEMSON, S.C. – James Davis ran for 143 yards and two touchdowns to lead three Clemson rushers with over 100 yards as the 18th-ranked Tigers beat Louisiana Tech 51-0 victory Saturday.

No. 20 California 41, Oregon St. 13

CORVALLIS, Ore. – Nate Longshore threw for 341 yards and four touchdowns, including two to Marshawn Lynch, and California coasted.

Lynch finished with three touchdowns for the Bears (4-1, 2-0 Pac-10), running 15 yards for another score.

No. 21 Nebraska 39, Kansas 32

LINCOLN, Neb. – Cody Glenn scored from a yard out in the first overtime and No. 21 Nebraska, which blew a 17-point lead, held Kansas out of the end zone for a 39-32 victory on Saturday night.

No. 22 Boise St. 36, Utah 3

SALT LAKE CITY – Jared Zabransky passed for 210 yards and a touchdown and ran for a score in what turned into an easy win for Boise State.

No. 25 Missouri 28, Colorado 13

COLUMBIA, Mo. – Missouri is off to its best start in a quarter-century.

Chase Daniel threw four touchdown passes to lead the Tigers, 5-0 for the first time since 1981. The Buffaloes (0-5, 0-1 Big 12), meanwhile, have lost nine straight.

– their longest losing streak since a 10-game slide during the 1963 and 1964 seasons.