Vladimir Guerrero Jr. celebrates his three-run homer with Santiago Espinal during Toronto’s 13-1 win over the Red Sox on Thursday night at Fenway Park. Elise Amendola/Associated Press

BOSTON — Vladimir Guerrero Jr. hit a three-run homer all the way out of Fenway Park, Hyun Jin Ryu held Boston to two hits over six innings and the Toronto Blue Jays routed the Red Sox 13-1 on Thursday night.

Teoscar Hernández hit a two-run double for the Blue Jays, who tagged the Red Sox for 16 hits and scored in six of the first seven innings while building a 12-0 lead. Every Toronto starter had at least one hit and drove in at least one run as the Blue Jays went 9 for 20 with runners in scoring position. Cavan Biggio was the only Toronto starter who didn’t score a run.

Ryu (10-5) struck out five and didn’t walk a batter.

Bobby Dalbec hit an RBI double in the seventh for Boston. The Red Sox finished with just six hits.

The Blue Jays led 6-0 in the fifth with two runners on for Guerrero, who crushed his 33rd homer of the season when reliever Phillips Valdez started him with a change-up. The ball cleared the Green Monster as well as a billboard above it by several yards on its way to Lansdowne Street.

The Blue Jays split the four-game series at first-place Boston, which still leads the AL East heading to second-place Tampa Bay for a weekend series.

The Red Sox didn’t score until the seventh inning, when Dalbec doubled off the wall in center field to drive in Christian Vázquez, whose one-out double off of reliever Tayler Saucedo was just the third hit of the night for Boston.

Eduardo Rodríguez (7-6) got roughed up early, allowing Teoscar Hernández’s bases-loaded double as Toronto scored three in the first inning on four hits and a walk. Rodríguez pitched 3 1/3 innings, allowing six runs on seven hits and four walks. He struck out eight.

NICE D

Although there was little to cheer defensively for Boston, Hunter Renfroe prevented further damage when he robbed Randal Grichuk of a homer to right in the fourth inning. Renfroe ran down the ball and held on when he slammed hard into the low wall with his left hip. Boston’s Alex Verdugo also reached over the wall in left the following inning to catch a foul by Biggio.

HEADING HOME

The Blue Jays will finally be back at home – meaning Toronto – this weekend.

The coronavirus pandemic and health protocols have kept the Blue Jays south of the Canadian border the past two seasons as they played “home” games in Buffalo, New York, and Dunedin, Florida, but the club was headed back home after the game and scheduled to host the Kansas City Royals on Friday night.

TRAINER’S ROOM

Blue Jays: Outfielder Lourdes Gurriel Jr. was out of the lineup after leaving Wednesday night’s game in the seventh inning after he took a pitch off his left elbow. Manager Charlie Montoyo said X-rays did not show a break and Gurriel would be day-to-day.

Red Sox: Right-hander Tanner Houck was optioned to Triple-A Worcester, one day after the rookie struck out seven over four innings in a start as Boston won to earn a split in a doubleheader. Houck allowed one run on two hits with one walk and had a 2.45 ERA in four starts for Boston. He is expected back soon and is tentatively scheduled to start one of the games during a doubleheader a week from Saturday at Toronto. “He’s going to be a big part of what we’re trying to accomplish. He’s a big part of it already,” Red Sox Manager Alex Cora said.

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