FORT MYERS, Fla. (AP) – Johan Santana vs. Curt Schilling. Sounds like a potential matchup for Game 1 of a playoff series.

Both aces pitched effectively Sunday during Boston’s 6-1 victory over Santana and the Minnesota Twins.

Making his first start of spring training, Santana allowed one run and three hits in two innings. The two-time AL Cy Young Award winner walked three, struck out two and wriggled out of a first-inning jam.

“I’m glad my changeup and slider were down. That’s a good sign. The pitches felt fine,” Santana said.

Schilling, making his second start this spring, worked on his changeup – a pitch he might add to his repertoire this season, Red Sox manager Terry Francona said.

Schilling earned the win by pitching 3 1-3 innings in front of a sellout crowd of 7,937 at Hammond Stadium. He walked one, struck out one and gave up two hits while throwing 48 pitches. He allowed a solo homer to Michael Cuddyer in the fourth before leaving the game.

“He used all of his pitches,” Francona said. “He wanted to use the changeup. I thought it enhanced his other pitches. He threw a couple every once in a while where it looked like he was trying to force the issue. He really hasn’t thrown one over the course of his whole career.”

But at age 40, Schilling wants to make a change, Francona said.

“He’s got too good a feel for pitching not to make adjustments,” Francona said.

Schilling was runner-up to Santana for the 2004 AL Cy Young Award, and Santana took the honor again last year.

When they squared off Sunday, it was about as good a matchup as anyone could ask for in spring training.

“In the regular season, it’s different,” Santana said. “Today I threw what, 45 pitches? I don’t try to do anything different or anything special. It’s not like in the regular season. In spring training, you just try to get back in shape and work on all of your pitches.”

Santana issued consecutive walks to Julio Lugo and Kevin Youkilis to start the game. Later in the inning, the left-hander walked Manny Ramirez, loading the bases. But Santana escaped, catching a line drive by Coco Crisp and then striking out Wily Mo Pena.

“Jo was a little erratic early,” Twins manager Ron Gardenhire said. “He was just trying to get a feel for the plate. He finds a way to get through the lineup. That’s what he does best.”

Scott Baker of the Twins gave up five runs in two innings, inflating his spring ERA to 24.30.