BUFFALO, N.Y. – Duke’s done.

Eric Maynor hit a 15-foot jumper with 1.8 seconds left to give Virginia Commonwealth a 79-77 upset victory over the Blue Devils in the first round of the NCAA tournament Thursday night. Maynor finished with 22 points, six in the final 1:24.

Duke lost a first-round game for the first time since 1996. The loss also ended the Blue Devils’ string of Sweet 16 appearances at nine.

Fittingly, it was VCU (28-6) that knocked off George Mason – the tournament’s surprise team last year – in the Colonial Athletic Association championship game. Maynor sealed that 65-59 win by scoring nine of his 20 points in the final 2 minutes.

Greg Paulus scored a career-high 25 points for Duke, seeded sixth in the West Regional. Josh McRoberts added a career-high 22 points and had 12 rebounds.

Jesse Pellot-Rosa’s 16-foot jumper gave VCU a 72-71 lead with 2:03 remaining. The Blue Devils (22-11) tied it three times, the last time at 77 when DeMarcus Nelson went coast-to-coast to hit a layup with 10.3 seconds left.

Maynor took the ensuing inbound pass and carried the ball across center court. Driving to the paint, he pulled up and hit a perfect jumper from just above the foul line.

Pittsburgh 79, Wright State 58

BUFFALO, N.Y. – No first-round exit this time for Pittsburgh.

The Panthers, ousted in the first round seven times in 18 previous appearances in the NCAA tournament, used their long-range marksmanship instead of their considerable brawn, hitting 10 of 21 3-pointers, and beat Wright State.

Ronald Ramon hit four 3s and finished with 14 points, and Sam Young had 13 to lead the Panthers, who never trailed.

Pittsburgh built 13-point leads three times in the first half against Wright State (23-10), hitting seven of 12 3-pointers and forging a 43-30 at the break.

UCLA 70, Weber St. 42

SACRAMENTO, Calif. – Arron Afflalo put an awful game behind him in UCLA’s impressive NCAA tournament opener.

Shaking off a terrible performance in last week’s Pac-10 tournament, Afflalo had 22 points and eight rebounds against Weber State (20-12).

Dezmon Harris led Weber State with 10 points.

Indiana 70, Gonzaga 57

SACRAMENTO, Calif. – Roderick Wilmont scored 22 points and hit six of his team’s nine 3-pointers, and the Hoosiers avenged a loss to Gonzaga last March.

Wilmont shot 8-for-16 and also added seven rebounds, three assists and a steal to extend his senior season for seventh-seeded Indiana (21-10), which was eliminated by the Zags 90-80 in a second-round meeting a year ago.

David Pendergraft had 12 points and five rebounds and Sean Mallon 11 points and six boards for 10th-seeded Gonzaga (23-11).

Midwest regional

Maryland 82, Davidson 70

BUFFALO, N.Y. – Mike Jones scored 17, D.J. Strawberry added 12 points and Maryland overcame Stephen Curry’s 30 points for Davidson.

Reserve forward Bambale Osby added 11 points and played a key role in sparking an 11-4 run that put the Terps ahead 69-63 with 7:27 remaining.

Maryland (25-8) overcame an eight-point second-half deficit and outscored the Wildcats 24-11 over the final 10 minutes to advance to the second round for the 20th time in school history.

Jason Richards scored 11 points for Davidson (29-5). Curry fouled

Butler 57, Old Dominion 46

BUFFALO, N.Y. – When Butler needed a spark, Pete Campbell delivered.

Campbell hit three 3-pointers, his only baskets of the game, to spark a 17-0 run and help the Bulldogs get the win in the first round.

Fifth-seeded Butler (28-6), tournament-tested with six appearances in 11 years, set a school record for victories in a season.

Brandon Johnson scored 11 points for Old Dominion (24-9), which had won 12 of 13 games.

South regional

Ohio State 78, Cent. Connecticut 57

LEXINGTON, Ky. – Greg Oden had 19 points and 10 rebounds in his first NCAA tournament game, and Jamar Butler scored 17 for top-seeded Ohio State.

Oden earned his 12th double-double of the season. Ron Lewis added 13 as the Buckeyes (31-3) quickly dispatched the game but ultimately overmatched the Blue Devils (22-12).

Javier Mojica led Central Connecticut with 19 points.

Xavier 79, BYU 77

LEXINGTON, Ky. – Drew Lavender, a 5-foot-7 transfer from Oklahoma, made two floaters in the lane, then grabbed a crucial rebound and sank two free throws with 11 seconds left to help the ninth-seeded Musketeers beat eighth-seeded Brigham Young.

Justin Doellman scored 23 points and Lavender finished with 17 to help Xavier (25-8) advance beyond the first round for the fourth time in its last five NCAA appearances.

Xavier trailed by as many as nine before Lavender, Doellman and B.J. Raymond hit 3-pointers during a 16-3 run that turned a 52-44 deficit into a 60-55 lead. BYU (25-9) battled back to take a 73-71 lead with 2:10 to go, but couldn’t stop Lavender down the stretch.

Louisville 78, Stanford 58

LEXINGTON, Ky. – Louisville did just fine in its odd Kentucky home. Stanford seemed all too eager to flee back to the West Coast.

Playing at Rupp Arena – home to archrival Kentucky – Louisville got 16 points from both Edgar Sosa and David Padgett. Sixth-seeded Louisville bolted to a 41-13 lead in front of a highly partisan crowd.

Earl Clark and Derrick Caracter each had 12 points for Louisville (24-9), which was playing less than 80 miles from its campus.

Texas A&M 68, Penn 52

LEXINGTON, Ky. – Acie Law scored 20 points and the third-seeded Aggies got two key dunks from Joseph Jones and a game-clinching 3-pointer from Dominique Kirk to advance past upset-minded Penn.

Jones tied the game at 39 with a thundering dunk at the 11-minute mark, then added another dunk less than a minute later to give Texas A&M (26-6) the lead for good.

Penn opened the second half with a 21-6 run. Ibrahim Jaaber had a three-point play to tie the game at 37, then made a short jumper to give Penn its first and only lead.

Mark Zoller had 19 points for the Quakers (22-9).

East regional

Georgetown 80, Belmont 55

WINSTON-SALEM, N.C. – Jessie Sapp scored a career-high 20 points and Jeff Green added 15 to help second-seeded Georgetown get the win.

Sapp made a career-high four 3-pointers for the Hoyas (27-6), who advanced to the second round for the second straight year and will renew a one-time Big East rivalry Saturday when they face seventh-seeded Boston College.

Andrew Preston had 14 points for Belmont (23-10).

Michigan State 61, Marquette 49

WINSTON-SALEM, N.C. – Raymar Morgan scored eight of his 14 points during a dominating first half, and Michigan State’s suffocating defense was too much for Marquette.

Drew Neitzel and Marquise Gray added 12 points apiece for the ninth-seeded Spartans (23-11), who shot nearly 54 percent and never trailed.

Washington State 70, Oral Roberts 54

SACRAMENTO, Calif. – Kyle Weaver stole an inbounds pass beneath his own basket and dunked to barely beat the halftime buzzer – and what a momentum swing for Washington State.

Reserve Ivory Clark scored 19 points and Weaver had 10 points, eight rebounds and four assists, and third-seeded Washington State (26-7) won its first NCAA game in 24 years. The Cougars will play Vanderbilt in the second round.

Vanderbilt 77, George Washington 44

SACRAMENTO, Calif. – Shan Foster scored 18 points and led Vanderbilt’s impressive defensive effort in the first round of the East Regional.

George Washington (23-9) missed its first six shots and didn’t get a field goal for nearly 6 minutes.

The 11th-seeded Colonials then endured another 11-minute stretch without a basket, falling behind by 29 late in the first half.

Derrick Byars scored 12 points for the Commodores (21-11).

George Washington committed 20 turnovers.