ST. PETERSBURG, Fla. – The road-weary New York Yankees headed to their new home on a high note.

Andy Pettitte pitched into the eighth inning, Robinson Cano hit a two-run homer and Derek Jeter singled in the go-ahead run in the ninth to lead the Yankees over the Tampa Bay Rays 4-3 Wednesday.

Jeter also doubled in the eighth and scored the tying run on Johnny Damon’s double off J.P. Howell. He delivered the tiebreaking run against Troy Percival (0-1) following a one-out double to Cody Ransom.

New York concluded a nine-game, opening trip and returned home for Thursday’s debut of the $1.5 billion new Yankee Stadium, across 161st Street from the House that Ruth Built. CC Sabathia makes his first home start in pinstripes against his former team, the Cleveland Indians.

Indians 5, Royals 4

KANSAS CITY, Mo. – Travis Hafner’s second double keyed a three-run seventh inning, and the Cleveland Indians picked up their first road win of the year while avoiding a three-game sweep with a 5-4 victory over the Kansas City Royals on Wednesday.

Jensen Lewis (1-0) issued three straight walks in the bottom of the seventh but still got the victory in relief of Aaron Laffey. Kyle Farnsworth (0-2) gave up three runs while getting only one out in relief for the Royals.

Tigers 9, White Sox 0

DETROIT – Armando Galarraga threw 6 1-3 scoreless innings and Placido Polanco drove in three runs as the Detroit Tigers beat the Chicago White Sox 9-0 on Wednesday afternoon.

Galarraga (2-0) ended Chicago’s three-game winning streak, allowing four hits and two walks while striking out five. Jose Contreras (0-2) took the loss, giving up five runs – three earned – on five hits in 5 2-3 innings

National League

Cardinals 12, D-backs 7

PHOENIX – Ryan Ludwick homered and drove in three runs and the St. Louis Cardinals defeated the Arizona Diamondbacks 12-7 on Wednesday afternoon. Ludwick is batting .407 and has hit in all seven games he’s played this season. He singled home a run in the third inning and added a two-run homer in the sixth.

Phillies-Nationals ppd.

WASHINGTON – Steady rain has washed out the Philadelphia Phillies’ game at Washington, keeping the Nationals winless for at least one more day.

No makeup date for the Wednesday night game was announced.

The Nationals have lost their first seven games, all but one on the road, the only winless team left in the major leagues.

The pitching matchup scheduled for Wednesday will remain intact. Phillies right-hander Joe Blanton, who is 0-0 with a 15.75 ERA, will be opposed by Washington right-hander Shairon Martis, who is 0-0 with a 9.00 ERA.

Rockies 5, Cubs 2

CHICAGO – Jason Marquis hit a two-run single off Rich Harden to put Colorado ahead against his former team, then pitched the Rockies over the Chicago Cubs 5-2 Wednesday.

Marquis (2-0), who spent the previous two years with the Cubs, was booed during introductions before Monday’s home opener and again several times Wednesday. He hit a bases-loaded single in the second and allowed one run and five hits in seven innings.

Marlins 10, Braves 4

ATLANTA – Dan Uggla drove in three runs for the second straight game and the Florida Marlins continued their strong start, beating the Atlanta Braves 10-4 on Wednesday night.

At 7-1, Florida has its best start since opening 1997 with eight wins in the first nine games. The Marlins snapped a 4-4 tie in the seventh on Peter Moylan’s bases-loaded walk to pinch-hitter Russ Gload. Moylan (0-1) gave up a leadoff single to Jorge Cantu, who scored the go-ahead run on Gload’s walk.

Mets 7, Padres 2

NEW YORK – Oliver Perez rebounded from a rough season debut and the New York Mets earned their first victory at Citi Field, beating the bumbling San Diego Padres 7-2 on Wednesday night.

Carlos Delgado homered and Perez pitched six smooth innings to help New York end San Diego’s five-game winning streak. The Padres spoiled Monday night’s opener at the $800 million ballpark with a 6-5 victory over the mistake-prone Mets.

Astros 4, Pirates 1

PITTSBURGH – Mike Hampton pitched six shutout innings and the Houston Astros snapped a five-game losing streak with a 4-1 victory over the Pittsburgh Pirates on Wednesday night. Hampton (1-1) allowed four singles, walked one and struck out eight. He improved to 11-3 in his career against Pittsburgh and has won seven consecutive starts against the Pirates.

Brewers 9, Reds 3

MILWAUKEE – The Milwaukee Brewers’ offense finally woke up, Mike Cameron hit a pair of home runs to spoil Micah Owings’ pitching debut for the Cincinnati Reds and the Brewers avoided a series sweep with a 9-3 victory Wednesday.

Milwaukee broke a 3-all tie with five runs in the sixth inning, getting an RBI double by Bill Hall, a two-run double by Jason Kendall and two-run homer by Rickie Weeks to take an 8-3 lead.