Buchholz (3-6) struck out eight and scattered three hits before Koji Uehara took over in the ninth and picked up his 11th save to preserve the shutout.

Mike Pelfrey (4-2) had a solid start as he and Buchholz both carried a shutout into the seventh inning, when the Red Sox broke the tie.

Xander Bogaerts hit a two-out double off the wall in center and scored easily on Castillo’s single up the middle.

Sandy Leon, who walked after Bogaerts’ double, was thrown out at third to end the inning, but the run counted and Buchholz put the Twins down in order in the eighth. Castillo saved a run in the top of the eighth with a catch on Aaron Hicks’ long fly to the base of the wall in right.

Buchholz got his first win since Boston beat Toronto 6-3 on May 10.

Pelfrey allowed one run and six hits, walking two and striking out one.

The Red Sox ended a dismal month of May by going 1-6 on a road trip, which included a three-game sweep by the Twins in Minneapolis last week.

Trainer’s room

Twins: Manager Paul Molitor said an MRI on RHP Ricky Nolasco’s right ankle showed no damage, but his return to the rotation remained uncertain. Molitor said Nolasco will do some throwing Thursday and the Twins will see how it goes.

Red Sox: RHP Justin Masterson (right shoulder tendinitis) is scheduled for his second rehab start Friday for Double-A Portland.

Up next

Twins: RHP Phil Hughes (4-4) makes his team-high 11th start to open a double-header set up when heavy rain Monday caused the series opener to be postponed.

RHP Trevor May (3-3) starts the night game.

Red Sox: LHP Eduardo Rodriguez (1-0) makes his second big-league start after throwing 7 2/3 shutout innings against Texas and winning his debut. Rodriguez scattered three hits and didn’t allow any runs.

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