INDIAN WELLS, Calif. (AP) – Defending champion Maria Sharapova was knocked out of the Pacific Life Open on Tuesday, a 4-6, 7-5, 6-1 loss to Vera Zvonareva that will cost her the No. 1 ranking.

Sharapova was beaten in the fourth round and needed to reach the Indian Wells semifinals to remain No. 1. She will be supplanted by Justine Henin when the rankings are released Monday. Henin, who is not at this tournament, won two recent events in the Middle East.

The 19-year-old Sharapova was playing her first event since withdrawing from her semifinal at Tokyo last month with a strained left hamstring.

She struggled in a match between Russians. Zvonareva, ranked No. 20, won for third time in seven matches against Sharapova.

Sharapova had 13 double-faults and 47 unforced errors. Zvonareva took control by winning eight consecutive games and 10 of the final 11. Frequently looking off-balance while serving, Sharapova bounced her second serve into the net on one of her two double-faults in losing the sixth game of the third set.

The men’s side of the tournament lost its No. 1 player Sunday when Guillermo Canas upset Roger Federer 7-5, 6-2 to end the Swiss star’s 41-match winning streak.