BOSTON – Tim Wakefield finally got plenty of support even though he didn’t need it.

David Ortiz and Mike Lowell drove in three runs each, Doug Mirabelli homered and drove in two and the Boston Red Sox beat the Los Angeles Angels 10-1 on Friday night after falling behind 1-0.

Wakefield (1-1) allowed one run in seven innings in his second solid outing of the season. He was even better in his other start this season but lost 2-0 on April 6 when the Red Sox managed only three hits against Texas, wasting his six-inning effort in which he gave up one earned run and three hits.

Last year, the Red Sox scored only six runs while he was in the game during his 11 losses. In five of those games, they didn’t score a single run for him.

The outlook wasn’t much brighter early on Friday, when he allowed one run on five hits and two walks in seven innings. In their previous game, Boston lost 3-0 on a one-hitter by Seattle’s Felix Hernandez. The Red Sox entered Friday’s game with a .238 batting average, ranked ninth in the AL.

They started slowly, trailing 1-0 on Vladimir Guerrero’s RBI single in the fourth. But they went ahead 2-1 in the fifth against John Lackey (2-1) on Mirabelli’s first homer of the season and an RBI single by Ortiz, who had struck out in his first two at bats.

Mirabelli, the light-hitting personal catcher for knuckleballer Wakefield, singled in a run in the sixth off Lackey and Mike Lowell made it 4-1 with a sacrifice fly off Darren Oliver in the seventh.

The Red Sox added six runs in the eighth off Oliver and Greg Jones on two-run doubles by Ortiz and Lowell and a two-run single by Drew.

Wakefield doesn’t get the publicity that Boston’s top three starters – Curt Schilling, Josh Beckett and Daisuke Matsuzaka – receive. And Mirabelli doesn’t get as much playing time as starter Jason Varitek.

Mirabelli had returned to Boston from San Diego early last season after catcher Josh Bard had 10 passed balls in Wakefield’s first four starts. Rather than wait for Bard to improve, the Red Sox reunited Wakefield with Mirabelli, who had caught him for much of the previous four seasons.

Mirabelli even got a police escort from Logan Airport after the trade was made last May 1 so he could catch Wakefield that night. He arrived at Fenway Park 13 minutes before that game and threw out a runner trying to steal. He had no passed balls Friday.

Blue Jays 2, Tigers 1

TORONTO – Roy Halladay pitched a six-hitter and Alex Rios hit a sacrifice fly in the 10th inning to lift the Toronto Blue Jays to a 2-1 victory over the Detroit Tigers on Friday night.

Halladay (2-0) struck out two and walked none. He threw 107 pitches to become the first pitcher with a 10-inning complete game since Mark Mulder pitched St. Louis to a 1-0 victory over Houston on April 23, 2005, according to the Elias Sports Bureau.

Jeremy Bonderman matched Halladay for much of the game. The Tigers right-hander allowed one run and six hits in nine innings. He struck out four and walked none.

Aaron Hill led off the 10th with an infield single off Fernando Rodney (1-2). Jason Smith bunted back to Rodney, who tried to flip the ball to first from his glove but couldn’t get it there in time, putting runners at first and second.

John McDonald followed with a bunt toward third base. Rodney fielded the ball but Brandon Inge had broken in and wasn’t on the bag. McDonald’s hit loaded the bases for Rios, who hit a fly ball to center that scored Hill.

Orioles 8, Royals 1

BALTIMORE – Erik Bedard pitched six innings of five-hit ball, and the Baltimore Orioles’ struggling offense struck early and late in an 8-1 victory over the Kansas City Royals on Friday night.

Baltimore provided Bedard with a 4-0 lead after three innings, and Nick Markakis sealed the win with his first career grand slam in the eighth against Todd Wellemeyer.

Aubrey Huff had two hits, two RBIs and scored a run for the Orioles, who scored a total of four runs in their previous three games.

Bedard (2-1) didn’t have a 1-2-3 inning until the sixth. He gave up one run, struck out nine and walked four in lowering his ERA from 6.94 to 5.09.

After Bedard threw 102 pitches, Orioles manager Sam Perlozzo turned the game over to a bullpen that received a $42 million makeover during the offseason. Chad Bradford retired Mark Grudzielanek on a grounder with two on and two out in the seventh, Danys Baez worked the eighth and Brian Burres finished.

Kevin Millar had two singles and two walks for Baltimore, which had 12 hits after entering the game with a .226 team batting average.

Devil Rays 4, Twins 2

MINNEAPOLIS – Johan Santana’s amazing Metrodome winning streak finally ended against Tampa Bay. Don’t be that surprised, though, because these Devil Rays can hit.

Carl Crawford’s inside-the-park home run and Scott Kazmir’s eight sharp innings helped Tampa Bay beat Santana and the Minnesota Twins 4-2 on Friday night.

Despite striking out 10 in seven innings, including five of the last six batters he faced, Santana (2-1) lost at home for the first time since Aug. 1, 2005. He was 17-0 during that stretch, and the Twins won all 24 games their two-time Cy Young Award winner pitched.

Santana gave up six hits, four runs and one walk.

, which came in a three-run fifth by the Devil Rays – who erased a 10-game losing streak at Minnesota. This was their first victory here since June 3, 2004, when Santana was also the victim.