TORONTO (AP) — Jon Lester struck out 11 in seven innings to win his fourth straight decision, Marco Scutaro and David Ortiz each matched a career-high with four hits and the Boston Red Sox beat the Toronto Blue Jays 14-0 Tuesday night.

Lester (15-6) allowed just three hits, all singles, and walked one to improve to 4-0 with a 1.16 ERA in five starts since losing at Minnesota on Aug. 10. He also matched a season high for strikeouts and is 4-0 in his last six starts against Toronto.

Jarrod Saltalamacchia and Josh Reddick homered as the Red Sox matched a season-high with 20 hits and scored at least two runs in each of the first five innings. It was the first time in franchise history Boston has achieved the feat, according to research by the Elias Sports Bureau provided to the Blue Jays.

Kyle Weiland pitched the final two innings for Boston.

Toronto lost for the fourth time in five games and 10th in the last 15.

After losing 1-0 in 11 innings in the series opener on Monday, the Red Sox jumped on Blue Jays left-hander Luis Perez (3-3) for four runs while batting around in the first inning. Adrian Gonzalez hit an RBI double, Ortiz and Scutaro had back-to-back RBI singles and Carl Crawford capped it with a run-scoring double.

Gonzalez singled home a run in the second and Kevin Youkilis followed with an RBI double but was thrown out trying to advance to third.

Boston made it 8-0 in the third on Saltalamacchia’s 15-homer, a two-run drive to center. Perez left three batters later after Dustin Pedroia reached on an error by Blue Jays third baseman Brett Lawrie.

Perez, winless in three starts, allowed a career-high eight runs and 10 hits in 2 2-3 innings. He walked two and struck out one.

Boston piled on with three more against left-hander Rommie Lewis in the fourth. Ortiz and Scutaro hit consecutive RBI doubles and, two outs later, Darnell McDonald drove in Scutaro with a single to right.

Scutaro made it 13-0 in the fifth with a two-run double off Dustin McGowan, who was pitching in the majors for the first time since July 8, 2008. The oft-injured right-hander had been sidelined by two shoulder surgeries and one knee surgery over the past three years.

After replacing Jacoby Ellsbury in the sixth, Reddick made it 14-0 with a solo drive to right off McGowan in the eighth.

McGowan allowed three runs and five hits in four innings. He walked three and struck out five.

Boston infielder Nate Spears made his major league debut in the fifth, replacing Crawford. Jed Lowrie, sidelined for the past two games with a sore left shoulder, came on for Gonzalez in the seventh.

Sprained ankle sidelines Beckett

TORONTO — Boston Red Sox right-hander Josh Beckett has a sprained right ankle and will miss his next scheduled start.

Beckett left in the fourth inning of Monday’s start at Toronto after experiencing pain in his ankle on consecutive pitches. He flew back to Boston on Tuesday to be examined by a specialist.

Red Sox medical director Dr. Tom Gill said in a statement that Beckett’s “examination was consistent with an ankle sprain,” adding that an MRI revealed no damage to Beckett’s ankle tendons or his Achilles’ tendon.

He will be re-evaluated later this week.

Red Sox manager Terry Francona said Beckett will miss his start Sunday at Tampa Bay. John Lackey will pitch Friday in place of Erik Bedard (left knee), Kyle Weiland will go Saturday and Jon Lester will pitch Sunday.

An All-Star for the third time this season, Beckett is 12-5 in 27 starts.

His 2.49 ERA is tied with Los Angeles Angels right-hander Jered Weaver for second-lowest in the AL, behind Detroit’s Justin Verlander (2.34).