PHILADELPHIA – Jason Bay and Jacoby Ellsbury homered, Julio Lugo had four hits, and the Boston Red Sox overcame another shaky outing by Daisuke Matsuzaka to beat the Philadelphia Phillies 11-6 on Saturday night.

The Red Sox have won the first two games in an interleague matchup between division leaders. They’ll go for the sweep Sunday with ace Josh Beckett on the mound.

Raul Ibanez hit his 22nd homer, and Pedro Feliz and Jayson Werth also connected for the Phillies, who’ve lost two straight since returning from a 7-3 road trip. The defending World Series champions are a major league-best 23-9 on the road, but they’re only 12-16 at Citizens Bank Park.

Hideki Okajima (3-0) allowed one run in two innings to earn the victory. Four Red Sox relievers gave up two runs in five innings after Matsuzaka lasted four, allowing four runs and seven hits. After going 18-3 last year, Dice-K is 1-4 with a 7.55 ERA.

Phillies starter Antonio Bastardo (2-1) gave up five runs – four earned – and three hits in one inning. The hard-throwing lefty didn’t return after a rain delay of 1 hour, 35 minutes.

Mets 6, Yankees 2

NEW YORK – Injury fill-in Fernando Nieve earned his first major league victory in three years, Omir Santos drove in three runs and the New York Mets bounced back from a discouraging loss with a 6-2 victory Saturday.

Gary Sheffield homered for the second straight day against his former team and Santos hit a two-run shot off Andy Pettitte (6-3).

Cardinals 3, Indians 1

CLEVELAND – Albert Pujols hit two home runs to lead the St. Louis Cardinals to a 3-1 win over the Cleveland Indians on Saturday. Pujols’ 27th multihomer game and fourth this season helped Brad Thompson (1-2) get his first win since St. Louis’ final game in 2008.

Rays 8, Nationals 3

ST. PETERSBURG, Fla. – Ben Zobrist and Gabe Gross homered during a seven-run sixth inning for Tampa Bay.

Carlos Pena hit his 20th home run for Tampa Bay. The defending AL champion Rays moved two games over .500 for the first time this season.

Andy Sonnanstine (5-6), who retired 15 batters in a row at one point, gave up three runs and six hits over 7 1-3 innings.

Pirates 9, Tigers 3

PITTSBURGH – Freddy Sanchez hit a grand slam and Adam LaRoche added a solo home run. Zach Duke (7-4) won for the fourth time in his past five decisions. He gave up three runs in eight innings and overcame solo homers by Marcus Thames and Ryan Raburn.

Sanchez hit his second career slam in the fourth inning to give the Pirates an 8-2 lead. LaRoche homered in the second when the Pirates scored four times off Armando Galarraga (3-7).

White Sox 7, Brewers 1

MILWAUKEE – Jose Contreras allowed two hits over eight scoreless innings and the White Sox battered struggling starter Manny Parra with a six-run outburst.

Contreras (2-5) struck out eight and walked two, using his array of arm angles and breaking pitches to frustrate the free-swinging Brewers. Since returning from a monthlong demotion to the minors, Contreras has given up just three hits in 16 scoreless innings. He earned his first road win since May 14, 2008. its lone run.

Twins 2, Cubs 0

CHICAGO – Rookie Anthony Swarzak scattered four hits over seven innings, Jason Kubel homered and the Twins hung on.

Minnesota got its runs in the early going against the returning Rich Harden (4-3) after a 32-minute rain delay at the start. Kubel led off the second with his 11th homer and Joe Maurer singled in a run, delighting the Twins fans.

The two-time defending NL Central champions simply couldn’t get anything going against Swarzak (2-2), who earned his first win since beating Milwaukee in his debut last month. The 23-year-old right-hander was sent down to the minors after the game.

Marlins 6, Blue Jays 5

TORONTO – Cody Ross homered and doubled twice to help rookie Sean West get his second major league win.

Jeremy Hermida also homered as the Marlins won their seventh straight game at Toronto. Florida is 16-4 all-time against the Blue Jays.

West (2-1) allowed four runs in 5 2-3 innings. In his previous start, he pitched eight shutout innings to beat San Francisco for his first big league victory.

Orioles 8, Braves 4

BALTIMORE – Brian Roberts had four hits, including a double that highlighted a six-run rally in a messy seventh inning.

The Orioles, who had lost 10 of their previous 12, scored their most runs in the past 16 games. A wild pitch, an error and two walks helped the Orioles’ comeback.

Royals 7, Reds 4

KANSAS CITY, Mo. – Willie Bloomquist had three hits and three RBIs and Billy Butler had three hits and drove in two runs and the Kansas City Royals defeated the Cincinnati Reds 7-4 Saturday night.

The Royals won back-to-back games for the first time since May 17-19. By winning the first two games over the Reds, the Royals have won a series for the first time since May 5-6, going 0-9-1 in their previous 10 series.

Kyle Davies (3-6), who was 0-5 with two no-decisions in his previous seven starts, picked up his first victory since April 30. Davies gave up two hits, but walked five and hit a batter in allowing three runs in five-plus innings.