BOSTON (AP) – Frank Thomas hit his 490th homer, a go-ahead, two-run drive off Tim Wakefield in the sixth inning that led the Toronto Blue Jays over the Boston Red Sox 7-3 on Monday night.

Aaron Hill had four hits, including a two-run homer in the ninth, as Toronto ended a five-game losing streak and stopped Boston’s five-game winning streak. Hill has four homers in 19 games after getting six in 155 last year.

Tomo Ohka (1-2) allowed three runs – two earned – and six hits in five-plus innings to win in a rematch of Boston’s 4-1 victory at Toronto last Wednesday. It was his first win in eight starts since Aug. 24 at Colorado.

Jason Frasor, filling in for injured closer B.J. Ryan, got his second save in two chances.

Wakefield gave up four runs – three earned – and eight hits in six innings. His ERA rose from an AL-best 1.35 to 2.08.

A day after tying a major league record with four straight homers against the New York Yankees, Boston didn’t hit any.

Boston’s Mike Lowell went 2-for-3 to improve his batting average to .323 but the third baseman continued his struggles in the field. His error in the second was his sixth in 36 chances. He has just six errors all last season when he had 462 chances and was second in AL fielding percentage to Oakland’s Eric Chavez.

Dustin Pedroia, 1-for-28 before getting two hits Sunday, put Boston ahead 2-1 with a two-run double in the fourth. Wakefield allowed just four runs in 25 innings entering the sixth, when he gave up Thomas’ third homer of the season – his second against the Red Sox – and Jason Phillips’ RBI single.

Boston cut the lead to 4-3 when Lowell scored on shortstop Royce Clayton’s throwing error in the sixth. Adam Lind hit a sacrifice fly in the eighth.

Notes: Ryan (elbow) was moved from the 15-day to the 60-day DL. … Boston CF Wily Mo Pena struck out in five straight at-bats before hitting into a forceout in the fourth. … John McDonald had three hits for Toronto. … Boston’s Julio Lugo went 0-for-5 and is in a 2-for-23 slump.