BOSTON (AP) – Manny Ramirez ended his longest homerless drought to start a season with a grand slam and a two-run shot, and Matt Clement won in his Fenway Park debut to lead the Boston Red Sox over the Tampa Bay Devil Rays 6-2 Saturday night.

Ramirez hit a two-run shot in the third inning, his 39th at-bat this season. In 2003, he didn’t connect until his 35th at-bat. He hit the 18th grand slam of his career in the sixth.

Alex Gonzalez went 4-for-4 with a double and three singles for the Devil Rays.

Clement (1-0), signed as a free agent during the offseason after pitching for the Cubs last year, gave up one run and seven hits while striking out six and walking two in seven innings. Boston grabbed a 2-1 lead in the third when Ramirez homered over the seats above the Green Monster. Johnny Damon singled leading off, then moved to third on consecutive wild throws by Dewon Brazelton. The first was on an errant pickoff attempt, and then he threw a wild pitch.

Ramirez entered the night hitting just .211 with four RBIs.

Ramirez’s slam made it 6-1 in the fourth. He lined a shot into the left-field seats after walks to Bill Mueller and Mark Bellhorn, and a single by Trot Nixon. His 18 slams are the most among active players and tied for third all-time with Robin Ventura and Willie McCovey. Lou Gehrig leads with 23.

Brazelton (0-3) remained winless in his career on the road, dropping to 0-12 in 16 starts. He allowed six runs on six hits in 3 2-3 innings while walking six and striking out one. Toby Hall’s RBI single gave Tampa Bay a 1-0 lead in the second.

Notes: It was Ramirez’s 40th career multihomer game. … Tampa Bay’s Jorge Cantu doubled in the second, extending his season-opening hitting streak to 11 games, second longest in Devil Rays’ history. behind Rocco Baldelli’s 13 in 2003. … Brazelton is 0-7 in his last 10 starts. … Kevin Millar is two for his last 23 at-bats. … The crowd cheered when a note was flashed on the center-field board with the Yankees’ loss and their worst start since 1991.

AP-ES-04-16-05 2217EDT