BAR HARBOR (AP) – Researchers say a genetic defect that causes a severe immune deficiency in humans may also produce balance disorders.

A study by researchers at the University of Iowa, the Jackson Laboratory in Maine and East Carolina University was funded in part by grants from the National Institutes of Health, and published online Friday in the Journal of Clinical Investigation.

The study examined a specialized strain of Jackson Lab mice that eliminates production a protein called p22phox. Disruption of that protein causes a severe immune deficiency in humans.

Dr. Botond Banfi, the senior author from Iowa, says it could open the door to further study of the consequences of the loss of balance.

AP-ES-02-25-08 1201EST


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