CLEVELAND – C.C. Sabathia outpitched Greg Maddux in a matchup of Cy Young winners, and the Cleveland Indians defeated the San Diego Padres 7-3 on Sunday.

Ben Francisco hit a three-run homer and Grady Sizemore a solo shot, his ninth homer in 16 games, as Cleveland took two of three in the interleague series.

Coming off a five-hitter against Minnesota on Tuesday, Sabathia (5-8) struck out 10 and allowed three runs and six hits over eight innings. His 14th game of double-digit strikeouts helped him past Charles Nagy for fifth place in Indians history with 1,239.

Maddux (3-5) fell to 0-2 in seven starts since May 10, when he became the ninth pitcher to win 350 games. The 42-year-old didn’t issue a walk for the seventh time in 15 starts this season, but wasn’t as sharp as usual. The four-time NL Cy Young winner hit a batter, threw a wild pitch, and even made an uncharacteristic error that led to three unearned runs.

Yankees 13, Astros 0

HOUSTON – Chien-Ming Wang pitched five scoreless innings before spraining his right foot running the bases, and Alex Rodriguez hit a three-run homer in New York’s rout of Houston.

Rodriguez hit his 185th homer as a Yankee later in the New York sixth, tying Paul O’Neill for 16th on the franchise’s all-time list. Rodriguez reached 1,540 RBIs on the home run, passing Joe DiMaggio and tying Willie Stargell for 40th all-time.

Rockies 5, White Sox 3

CHICAGO – Brad Hawpe hit a go-ahead home run, Aaron Cook earned his career-high 10th win and Colorado hung on to beat Chicago.

The White Sox loaded the bases against Brian Fuentes in the ninth on Juan Uribe’s leadoff single and two two-out walks. With two outs, Joe Crede hit a pop fly to left that Matt Holliday nearly dropped as he avoided colliding with shortstop Carlos Quintanilla.

Holliday made a barehanded catch, cradling the ball against his chest and the Rockies escaped with their eighth win in 11 games.

Cubs 7, Blue Jays 4

TORONTO – Ted Lilly allowed one hit over six scoreless innings, Derrek Lee drove in three runs and Aramis Ramirez homered for the Cubs.

Lilly (7-5) won for the sixth time in seven decisions dating to May 3 and has a 3.81 ERA over that span. He struggled with his control but kept wiggling out of jams.

Rangers, Mets split

NEW YORK – Pedro Martinez pitched six sharp innings, pinch-hitter Robinson Cancel got his first major league hit in nearly nine years and the Mets salvaged a split of a doubleheader.

Billy Wagner ended his skid of three straight blown saves and David Wright had three hits for his first multihit game in two weeks for the Mets. Carlos Beltran followed up a homer and two RBIs in the opener with a run-scoring single as New York took two of three from Texas, perhaps giving Mets manager Willie Randolph a reprieve from being fired.

Martinez (2-0) was making his first start at Shea Stadium since Sept. 27.

Tigers 5, Dodgers 4

DETROIT – Nate Robertson pitched six shutout innings, Marcus Thames and Brandon Inge hit back-to-back homers and Detroit won its sixth straight.

Robertson (5-6) allowed four hits and walked none, winning for the fourth time in five starts. Carlos Guillen had three hits and an RBI for Detroit, which finished with 14 hits.

The Dodgers scored four runs in the ninth inning but Todd Jones got Juan Pierre to fly out to center with a runner on second to earn his 12th save.

Cardinals 7, Phillies 6

ST. LOUIS – Rick Ankiel scored from second on the Philadelphia Phillies’ second error at first base in the 10th inning, giving St. Louis the win over Philadelphia in a National League matchup.

Ankiel reached with two outs on second baseman Chase Utley’s wild throw to reliever Tom Gordon, who was covering the bag. After Troy Glaus singled, Gordon (5-4) again had to cover the bag on Chris Duncan’s grounder between first and second. He missed the ball as he ran across the base.

Marlins 9, Rays 3

ST. PETERSBURG, Fla. – Ricky Nolasco came within one out of the first complete game of his career, and Mike Jacobs and Wes Helms hit three-run homers Sunday to power the Florida.

Nolasco (7-4) allowed three runs and six hits to win for the sixth time in his past seven decisions and tie Mark Hendrickson for the team lead in victories. The right-hander struck out a career-high 12 and walked one.

Brewers 4, Twins 2

MILWAUKEE – Mike Cameron hit a two-run homer, Seth McClung scattered four hits and the Brewers snapped a six-game losing streak in interleague play dating to last season.

Relievers Brian Shouse, Guillermo Mota and Salomon Torres, who picked up his eighth save, each pitched a hitless inning after the bullpen gave up 13 runs the last two games.

Pirates 5, Orioles 4

BALTIMORE – Adam LaRoche singled in the tiebreaking run off George Sherrill in the 10th inning, and the Pirates beat Baltimore 5-4 to end a run of seven straight interleague defeats.

Brian Roberts hit a tying homer for Baltimore in the ninth, but the Orioles couldn’t complete a three-game sweep during a series in which they repeatedly fought from behind.

Athletics 5, Giants 3

SAN FRANCISCO – Eric Chavez had three hits and two RBIs to help Oakland complete its second consecutive sweep of San Francisco.

Dana Eveland (5-5) gave up a run and six hits in 6 2-3 innings for the A’s, who have won six straight over the Giants and four of five overall. The left-hander walked three and struck out five in his first road win since April 25 at Seattle.

Huston Street pitched the ninth for his 13th save in 15 chances in the A’s first save opportunity in 17 games.

, their longest streak since the 1981 season.

Kevin Correia (1-4) was activated from the disabled list to make his first start since getting only one out on April 26 against the Cincinnati Reds. He went 5 1-3 innings, allowing five runs and seven hits. He walked two and struck out four as the Giants lost for the fifth time in six games.

Royals 8, Diamondbacks 3

PHOENIX – David DeJesus hit his first career grand slam and had a career-high five RBIs, helping the Royals win for the second time in three games against Arizona.

Gil Meche (4-8) went 7 1-3 innings for his first victory since May 15, a span of six starts. He allowed three runs on four hits, striking out a season-high 10 and walking one.

Micah Owings (6-5) went 5 1-3 innings, allowing a season-high seven runs and eight hits. He won his first four starts but has struggled since then, and has allowed 21 earned runs in 19 innings over his last four starts.

Nationals 6, Mariners 2

SEATTLE – Rookie Kory Casto’s pinch-hit, three-run homer off the foul pole broke an eighth inning tie and led Washington past Seattle.

The Nationals swept their first three-game series since last September and handed the Mariners their seventh consecutive home loss. It is the longest home losing streak for the Mariners since they lost eight straight in 1996 at the Kingdome.

Casto, who had been 0-for-14 in his previous five games, hit his first career homer came off reliever Mark Lowe (1-3). Washington recalled Casto on June 3 from Triple-A Columbus.

Reliever Jesus Colome (2-1) picked up the win. He threw two scoreless innings.