GRAY — The snow drought may come to an end: The National Weather Service on Tuesday issued a winter storm watch from late Wednesday through Thursday night.

Low pressure lifting out of the deep South could spread “significant snowfall” of 6 or more inches across much of Maine on Wednesday night, according to the Weather Service.

Temperatures will be in the low 20s and roads will quickly become snow-covered and slippery. Heavy snowfall at times could reduce visibility to a half-mile or less.

Slight changes to the storm’s track and strength “could yield significant difference in precipitation, but confidence is increasing for a ‘plowable’ snowfall along the foothills and interior,” the Weather Service reported.

The storm will begin Wednesday night as snow. By Thursday morning, warmer air could change the snowfall to a wintry mix with sleet or freezing rain. The storm is expected to end Thursday night with freezing drizzle.